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1-phenyl-2-nitropropene

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1-phenyl-2-nitropropene

Phenyl-2-nitropropene is a chemical compound with the chemical formula is C9H9NO2. It can be produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst. In this reaction, the base deprotonates nitroethane to form a resonance stabilized anion. This anion nucleophilically adds to the aldehyde forming a beta nitro alcohol, which is subsequently dehydrated to yield the nitroalkene. This reaction is known as a nitroaldol reaction. Phenyl-2-nitropropene is used to make pharmaceuticals. It is used in pharmaceutical industry to manufacture drug Adderall, an amphetamine mixture, which is used to treat ADHD and narcolepsy. Buy Phenyl-2-nitropropene online


Phenyl-2-Nitropropene : 1-phenyl-2-nitropropene

1 mol benzaldehyde, 1.2 mol nitroethane and 15 mL diluted aqueous methylamine in 150 mL alcohol. Stirred and slightly heated for ca 4 hours. The reaction mixture is brought over into a beaker and cooled in the fridge (4°C). If precipitation doesn’t commence at this point, water is poured in and the mixture put back in the fridge. The P2NP oil layer will slowly (or sometimes quickly) start forming a crystalline layer. If it doesn’t, scratching the wall with e.g. a glass rod will help. Phenyl-2-nitropropene buy Online Super Chemicals

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