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Cytokine And Cancer: Unravelling The Complex Relationship

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Vaishnavi Kashid
Cytokine And Cancer: Unravelling The Complex Relationship

The relationship between cytokines and cancer is complex and multifaceted. Cytokines can have both pro-tumorigenic and anti-tumorigenic effects, depending on the context and the specific cytokine involved.


While some cytokines, such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), can promote tumor growth and metastasis by enhancing angiogenesis, cell proliferation, and survival, other Cytokine, such as interferons and tumor necrosis factor-beta (TNF-β), exhibit anti-tumorigenic properties by stimulating immune responses and inducing cancer cell death.


The dysregulation of Cytokine in the tumor microenvironment plays a critical role in cancer development and progression. The intricate interplay between cancer cells and immune cells influences the production and activity of cytokines, shaping the immune response against tumors. Additionally, cytokines can modulate the tumor microenvironment, affecting tumor cell behaviour and response to therapy.


Unravelling the complex relationship between cytokines and cancer is essential for the development of effective cancer therapies. Targeting specific cytokines or their receptors has shown promising results in preclinical and clinical studies. Moreover, the measurement of cytokine levels in patients has potential as a diagnostic and prognostic tool, aiding in patient stratification and treatment decision-making. Continued research into Cytokine-cancer interactions will deepen our understanding of tumor biology and pave the way for novel therapeutic interventions.


Read More- http://wordoid01.weebly.com/cmi-article/the-impact-of-cytokine-on-autoimmune-disorders-a-comprehensive-review


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Vaishnavi Kashid
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